Evodia rutaecarpa herb information and research

Evodia rutaecarpa is a popular traditional Chinese medicine

Evodia rutaecarpa contains wuchuyuamide-I, quercetin, limonin, evodiamine and rutaecarpine. There is also acylgluconic acids, trans-feruloylgluconic acid and trans-caffeoylgluconic acid, together with myo-inositol, phthalic acid dibutyl este.

Toxicological assessment on safety of water and 70% ethanolic extracts of nearly ripe fruit of Evodia rutaecarpa
Zhongguo Zhong Yao Za Zhi. 2008 Jun; Yang XW. Department of Natural Medicines, State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing 100083, China.
To study the acute toxicity and mutagenic risk of the Evodia rutaecarpa water extracts and 70% Evodia rutaecarpa ethanol extracts (EREE) from the nearly ripe fruit of Evodia rutaecarpa, and provide experimental basis for safety evaluation of ones. The oral LD50 of the Evodia rutaecarpa water extracts and Evodia rutaecarpa ethanol extracts in mice was more than 10.0 g x kg(-1) belonging to non-toxicity on the acute toxicity rating criteria. Both Evodia rutaecarpa water extracts and Evodia rutaecarpa ethanol extracts showed no genotoxicity in the experimental condition.

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