Eugenia jambolana Jamun herb information
Eugenia jambolana seed has gastro-protective properties mainly through promotion of mucosal defensive factors and antioxidant status and decreasing lipid peroxidation.
Eugenia jambolana fruit extract
and breast cancer
Eugenia jambolana Lam. berry extract inhibits growth and induces apoptosis of human breast cancer but not non-tumorigenic breast cells.
J Agric Food Chem. 2009, Adams LS, Chen S, Killian C, Ahmed A, Seeram NP. Department of Biomedical and Pharmaceutical Sciences, Bioactive Botanical Research Laboratory, College of Pharmacy, University of Rhode Island, Kingston, Rhode Island, USA.
The ripe purple berries of the native Indian plant Eugenia jambolana Lam., known as Jamun, are popularly consumed and available in the United States in Florida and Hawaii. Despite the growing body of data on the cancer preventive potential of edible berry extracts, there is paucity of such data for Eugenia jambolana fruit. Therefore our laboratory initiated the current Eugenia jambolana study with the following objectives: To prepare a standardized Eugenia jambolana fruit extract for biological studies and to investigate the antiproliferative and pro-apoptotic effects of Eugenia jambolana fruit extract in estrogen dependent / aromatase positive (MCF-7aro), and estrogen independent (MDA-MB-231) breast cancer cells, and in a normal/nontumorigenic (MCF-10A) breast cell line. Eugenia jambolana fruit extract was standardized to anthocyanin content. Eugenia jambolana fruit extract contained 3.5% anthocyanins (as cyanidin-3-glucoside equivalents) which occur as diglucosides of five anthocyanidins / aglycons: delphinidin, cyanidin, petunidin, peonidin and malvidin. Our studies suggest that Eugenia jambolana fruit extract may have potential beneficial effects against breast cancer.
In vitro antiviral activity of plant extracts on goatpox virus replication.
Indian J Exp Biol. 2008; Bhanuprakash V, Hosamani M, Balamurugan V, Gandhale P, Naresh R, Swarup D, Singh RK. Division of Virology, Indian Veterinary Research Institute, Mukteswar, India.
Four plants having known medicinal properties were screened for inhibition of goatpox virus (GTPV) replication in vitro. Of the 4 plants, extract of Acacia arabica (Babul) and Eugenia jambolana ( Jamun ) leaves had inhibition (%) 99.70 and 99.92 at their maximum non toxic concentrations, 99 and 1999 microg/ml, respectively in all cytopathic effect (CPE) inhibition assays. Results indicated that the extract of Acacia arabica and Eugenia jambolana leaves inhibited GTPV replication in vitro.
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