Eugenia jambolana Jamun herb information
Eugenia jambolana seed has gastro-protective properties mainly through promotion of mucosal defensive factors and antioxidant status and decreasing lipid peroxidation.
Eugenia jambolana fruit extract
and breast cancer
Eugenia jambolana Lam. berry extract inhibits growth and induces apoptosis of
human breast cancer but not non-tumorigenic breast cells.
J Agric Food Chem. 2009 Feb 11; Li L, Adams LS, Chen S, Killian C, Ahmed A,
Seeram NP. Department of Biomedical and Pharmaceutical Sciences, Bioactive
Botanical Research Laboratory, College of Pharmacy, University of Rhode Island,
Kingston, Rhode Island, USA.
The ripe purple berries of the native Indian plant Eugenia jambolana Lam., known
as Jamun, are popularly consumed and available in the United States in Florida
and Hawaii. Despite the growing body of data on the cancer preventive potential
of edible berry extracts, there is paucity of such data for Eugenia jambolana
fruit. Therefore our laboratory initiated the current Eugenia jambolana study
with the following objectives: To prepare a standardized Eugenia jambolana fruit
extract for biological studies and to investigate the antiproliferative and
pro-apoptotic effects of Eugenia jambolana fruit extract in estrogen dependent /
aromatase positive (MCF-7aro), and estrogen independent (MDA-MB-231) breast
cancer cells, and in a normal/nontumorigenic (MCF-10A) breast cell line. Eugenia jambolana
fruit extract was standardized to anthocyanin content. Eugenia jambolana fruit
extract contained 3.5% anthocyanins (as cyanidin-3-glucoside equivalents) which
occur as diglucosides of five anthocyanidins / aglycons: delphinidin, cyanidin,
petunidin, peonidin and malvidin. Our studies suggest that Eugenia jambolana
fruit extract may have potential beneficial effects against breast cancer.
Anti-viral effects
In vitro antiviral activity of plant extracts on goatpox virus replication.
Indian J Exp Biol. 2008 Feb;
Bhanuprakash V, Hosamani M, Balamurugan V, Gandhale P, Naresh R, Swarup D, Singh
RK. Division of Virology, Indian Veterinary Research Institute, Mukteswar 263
138, India.
Four plants having known medicinal properties were screened for inhibition of
goatpox virus (GTPV) replication in vitro. Of the 4 plants, extract of Acacia
arabica (Babul) and Eugenia jambolana ( Jamun ) leaves had inhibition (%) 99.70
and 99.92 at their maximum non toxic concentrations, 99.93 +/- 0.38 and 1999.73
+/- 0.50 microg/ml, respectively in all cytopathic effect (CPE) inhibition
assays. Results indicated that the extract of Acacia arabica and Eugenia
jambolana leaves
inhibited GTPV replication in vitro.
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